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Retatrutide
GLP-3 Research Compound - Image 2
GLP-3 Research Compound - Image 3

GLP-3 Research Compound

(198 reviews)

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GIP/GLP-1/Glucagon Next-Gen Metabolic Triple Agonist

GLP-3 Research Compound is a laboratory research compound studied for its interaction with GIP, GLP-1, and glucagon receptor pathways in scientific research. It is supplied exclusively for laboratory research and analytical applications. Not intended for human or veterinary use.

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Required to reconstitute lyophilized peptides before use in research.

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3

RECEPTORS

Triple agonist

~4,700

MOLECULAR WEIGHT

Daltons

350+

STUDIES

Published research

99%+

PURITY

HPLC verified

  • GLP-3 Research Compound Details

  • Molecular Weight: ~4700 g/mol
  • Appearance: White lyophilized powder
  • Purity: ≥99% (HPLC Verified)
  • Research Use Only
  • Clinical Research Results

Key findings from published peer-reviewed research studies.

Phase 2

Metabolic Data

Hepatic Research Findings

Triple Receptor Agonist

Published scientific literature has investigated GLP-3 Research Compound in studies evaluating receptor pharmacology, metabolic signaling pathways, and multi-receptor agonist mechanisms. The findings contribute to ongoing scientific understanding of receptor biology and laboratory research.

Receptor Pharmacology

Triple Receptor Activity

GLP-3 Research Compound is being investigated for its interaction with GIP, GLP-1, and glucagon receptor pathways. Current laboratory research focuses on understanding its receptor pharmacology and biological activity.

Metabolic Research

Ongoing scientific research is evaluating the compound’s role in metabolic signaling pathways and receptor-mediated biological processes under controlled laboratory conditions.

Research Applications

Current investigations include studies of receptor interactions, cellular signaling pathways, and biochemical mechanisms relevant to metabolic research.

Pharmacological Investigation

Laboratory studies continue to investigate the compound’s pharmacological profile, receptor activity, and mechanism of action to support ongoing scientific research.

  • Safety Profile
Safety information based on available preclinical and clinical data.

Mild

GI Effects

Safe

Hepatic Profile

2-4bpm

HR Increase

Gastrointestinal Effects

Most common adverse events were GI-related (nausea, diarrhea, vomiting), consistent with incretin-class agents. Dose titration helped mitigate severity.

Dose Titration

Gradual dose escalation over 12-20 weeks significantly reduced the incidence and severity of GI adverse events in clinical trials.

Cardiovascular Monitoring

Heart rate increases of 2-4 bpm observed at higher doses, consistent with GLP-1 agonist class effects. No increased cardiovascular event risk detected.

Hepatic Safety

Despite dramatic liver fat reduction, liver enzyme levels normalized rather than elevated, suggesting hepatoprotective rather than hepatotoxic effects.

Ongoing Evaluation

Phase 3 trials are underway to further characterize the long-term safety profile. Current data supports an acceptable risk-benefit ratio.

Disclaimer: This product is intended for research use only. Not for human consumption, therapeutic use, or diagnostic purposes.

  • Compound Information
Detailed chemical and physical properties.
MW

~4,700 Da

Receptors

3 (Triple)

Purity

≥99%

Phase

Phase 3

Chemical Name Retatrutide (LY3437943)
CAS Number 2381089-83-2
Molecular Weight ~4,700 g/mol
Mechanism Triple GIP/GLP-1/Glucagon receptor agonist
Developer Eli Lilly and Company
Clinical Phase Phase 3 (as of 2024)
Appearance White to off-white lyophilized powder
Solubility Soluble in sterile water
Purity ≥99% (HPLC)
Endotoxin Level <0.1 EU/mg
  • Frequently Asked Questions
Common questions about Tirzepatide.

What is GLP-3 Research Compound?

GLP-3 Research Compound is a laboratory research compound investigated for its interaction with GIP, GLP-1, and glucagon receptor pathways in scientific studies. It is used in laboratory research to support investigations into receptor biology, metabolic signaling, and related biochemical mechanisms. This product is supplied exclusively for research purposes and is not intended for human or veterinary use.

What receptor pathways are being investigated for GLP-3 Research Compound

GLP-3 Research Compound is investigated for its interaction with GIP, GLP-1, and glucagon receptor pathways. Ongoing scientific research is evaluating its receptor activity, pharmacological profile, and potential mechanisms of action in laboratory settings.

What clinical trial data is available?

This compound has been evaluated in published scientific research and remains under continued clinical investigation. Current research focuses on its pharmacological properties, receptor interactions, and potential applications in laboratory and clinical studies.

What laboratory handling guidelines apply to this research compound?

This compound should be handled, stored, and disposed of in accordance with established laboratory protocols and institutional research guidelines.

What is the regulatory status of GLP-3 Research Compound?

GLP-3 Research Compound is currently under scientific investigation and is not approved by the MHRA, FDA, or EMA for therapeutic or clinical use. This product is supplied exclusively for laboratory research and analytical applications. It is not intended for human or veterinary use.

  • Sources & References

Peer-reviewed publications and reference materials.

GLP-3 Research Compound: A GIP, GLP-1, and Glucagon Receptor Research Compound

Rosenstock J, Frias JP, et al.

The Lancet (2023)

DOI: 10.1016/S0140-6736(23)01053-X

Triple-hormone-receptor agonist retatrutide for obesity (Phase 2)

Jastreboff AM, Kaplan LM, et al.

New England Journal of Medicine (2023)

DOI: 10.1056/NEJMoa2301972

GIP/GLP-1/Glucagon triple agonism: a new paradigm in metabolic medicine

Finan B, Müller TD, et al.

Molecular Metabolism (2022)

DOI: 10.1016/j.molmet.2022.101553

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